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    4
    Dec
    2012
    2:57pm, EST

    Kids' tantrums as disorder concern docs

    By Rachael Rettner, MyHealthNewsDaily 
    Some doctors are concerned about new guidelines allowing children who frequently throw tantrums to be diagnosed with a mental health disorder, arguing that normal kids can act this way, but also caution that such behavior could signal several other mental health conditions.

    The new diagnosis of "disruptive mood dysregulation disorder" will appear in the updated version of the psychiatric handbook the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), to be published in May. The American Psychiatric Association (APA) approved the final version of the manual on Saturday (Dec. 1).

    Although detailed criteria for the diagnosis have not been released, an APA statement said the condition could apply to "children who exhibit persistent irritability and frequent episodes of behavior outbursts three or more times a week for more than a year." The addition is intended in part to reduce the number of kids misdiagnosed as having bipolar disorder, who may be treated with powerful drugs.

    But some experts say the new condition was added to the manual too soon.

    "I think it's premature to put it in as a full diagnosis," said Dr. David Axelson, an associate professor of psychiatry at University of Pittsburgh School of Medicine, referring the condition's inclusion in the front of the manual with other well-accepted diagnoses, rather than in the appendix, which includes provisional diagnoses requiring further research.

    Some are concerned that a label of disruptive mood dysregulation disorder would turn normal kid behavior into a medical condition. [ See Typical Toddler Behavior, or ADHD? 10 Ways to Tell.]

    But Axelson said the diagnosis requires severe and frequent behavior problems, and if properly applied, kids without a true mental condition would be unlikely to be diagnosed. In addition to frequent outbursts for more than a year, children need to be at least 6, but younger than teenagers, to be given the diagnosis, according to early versions of the criteria.

    However, parents might overestimate how often their child behaves badly, because they focus on recent outbursts, and inaccurately reporting behavior to a mental health professional may lead to mislabeling, Axelson said.

    And although the diagnosis is intended to reduce misdiagnoses of childhood bipolar disorder and subsequent overtreatment, it could end up putting more kids on medication, Axelson said. That's because there are no treatments for the new condition, so doctors will likely prescribe medications for explosive anger — which are the same medications for bipolar disorder.

    Research suggests the new disorder could become common among kids already diagnosed with other mental conditions. A study by Axelson and colleagues, published in October, found that more than half of children with oppositional defiant disorder or conduct disorder met criteria for the condition, and it was hard to distinguish the disorders from each other.

    Also, the diagnosis was not particularly stable, meaning it was not repeatedly diagnosed in the same children over multiple evaluations. This counters the idea that the new condition is chronic, Axelson said.

    Some are concerned doctors will diagnose children with disruptive mood dysregulation disorder without checking for other mental problems.

    "Explosive behavior is like a high fever," said Dr. Gabrielle Carlson, a professor of psychiatry and pediatrics at Stony Brook University School of Medicine in New York. "If you have it, you know there's something wrong, but it doesn't tell you what's wrong."

    The focus could be taken off other conditions that can lead to explosive behavior, including attention deficit hyperactivity disorder, obsessive compulsive disorder and autism, Carlson said.

    But others see the move as positive. Lauren Wakschlag, a clinical psychologist at Northwestern University Feinberg School of Medicine who studies children's tantrums, said there are advantages to having this diagnosis for children's mood problems.

    Traditionally, these children may have been given any of several diagnoses, because tantrum behaviors overlap with those of other conditions.

    "Here, you have a unifying way to diagnose symptoms," Wakschlag said.

    However, because children's behavior can vary substantially between ages 6 and the teen years, more research is needed to determine how to diagnose children of particular ages, Wakschlag said.

    More from MyHealthNewsDaily:

    • Hypersex to Hoarding: 7 New Psychological Disorders
    • The Old Drug Talk: 7 New Tips for Today's Parents
    • 10 Ways to Promote Kids' Healthy Eating Habits 

    More from NBCNews.com health:

    • Most teens with mental disorders not on meds
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    49 comments

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  • 1
    Dec
    2012
    9:27pm, EST

    'Asperger's disorder' being dropped from psychiatrists' diagnostic guide

    The American Psychiatric Association announced a  revision to their diagnostic manual after almost two decades of consideration. TODAY contributor Dr. Gail Saltz discusses the changes, which include new guidelines for treating binge eaters and hoarders and the removal of Asperger's as a diagnosis.

    By Lindsey Tanner, The Associated Press

    CHICAGO -- The now familiar term "Asperger's disorder" is being dropped. And abnormally bad and frequent temper tantrums will be given a scientific-sounding diagnosis called DMDD. But "dyslexia" and other learning disorders remain.

    The revisions come in the first major rewrite in nearly 20 years of the diagnostic guide used by the nation's psychiatrists. Changes were approved Saturday.

    Full details of all the revisions will come next May when the American Psychiatric Association's new diagnostic manual is published, but the impact will be huge, affecting millions of children and adults worldwide. The manual also is important for the insurance industry in deciding what treatment to pay for, and it helps schools decide how to allot special education.

    This diagnostic guide "defines what constellations of symptoms" doctors recognize as mental disorders, said Dr. Mark Olfson, a Columbia University psychiatry professor. More important, he said, it "shapes who will receive what treatment. Even seemingly subtle changes to the criteria can have substantial effects on patterns of care."


    Olfson was not involved in the revision process. The changes were approved Saturday in suburban Washington, D.C., by the psychiatric association's board of trustees.

    The aim is not to expand the number of people diagnosed with mental illness, but to ensure that affected children and adults are more accurately diagnosed so they can get the most appropriate treatment, said Dr. David Kupfer. He chaired the task force in charge of revising the manual and is a psychiatry professor at the University of Pittsburgh.

    One of the most hotly argued changes was how to define the various ranges of autism. Some advocates opposed the idea of dropping the specific diagnosis for Asperger's disorder. People with that disorder often have high intelligence and vast knowledge on narrow subjects but lack social skills. Some who have the condition embrace their quirkiness and vow to continue to use the label.

    And some Asperger's families opposed any change, fearing their kids would lose a diagnosis and no longer be eligible for special services.

    But the revision will not affect their education services, experts say.

    The new manual adds the term "autism spectrum disorder," which already is used by many experts in the field. Asperger's disorder will be dropped and incorporated under that umbrella diagnosis. The new category will include kids with severe autism, who often don't talk or interact, as well as those with milder forms.

    Kelli Gibson of Battle Creek, Mich., who has four sons with various forms of autism, said Saturday she welcomes the change. Her boys all had different labels in the old diagnostic manual, including a 14-year-old with Asperger's.

    "To give it separate names never made sense to me," Gibson said. "To me, my children all had autism."

    Three of her boys receive special education services in public school; the fourth is enrolled in a school for disabled children. The new autism diagnosis won't affect those services, Gibson said. She also has a 3-year-old daughter without autism.

    People with dyslexia also were closely watching for the new updated doctors' guide. Many with the reading disorder did not want their diagnosis to be dropped. And it won't be. Instead, the new manual will have a broader learning disorder category to cover several conditions including dyslexia, which causes difficulty understanding letters and recognizing written words.

    The trustees on Saturday made the final decision on what proposals made the cut; recommendations came from experts in several work groups assigned to evaluate different mental illnesses.

    The revised guidebook "represents a significant step forward for the field. It will improve our ability to accurately diagnose psychiatric disorders," Dr. David Fassler, the group's treasurer and a University of Vermont psychiatry professor, said after the vote.

    The shorthand name for the new edition, the organization's fifth revision of the Diagnostic and Statistical Manual, is DSM-5. Group leaders said specifics won't be disclosed until the manual is published but they confirmed some changes. A 2000 edition of the manual made minor changes but the last major edition was published in 1994.

    Olfson said the manual "seeks to capture the current state of knowledge of psychiatric disorders. Since 2000 ... there have been important advances in our understanding of the nature of psychiatric disorders."

    Catherine Lord, an autism expert at Weill Cornell Medical College in New York who was on the psychiatric group's autism task force, said anyone who met criteria for Asperger's in the old manual would be included in the new diagnosis.

    One reason for the change is that some states and school systems don't provide services for children and adults with Asperger's, or provide fewer services than those given an autism diagnosis, she said.

    Autism researcher Geraldine Dawson, chief science officer for the advocacy group Autism Speaks, said small studies have suggested the new criteria will be effective. But she said it will be crucial to monitor so that children don't lose services.

    Other changes include:

    —A new diagnosis for severe recurrent temper tantrums — disruptive mood dysregulation disorder. Critics say it will medicalize kids' who have normal tantrums. Supporters say it will address concerns about too many kids being misdiagnosed with bipolar disorder and treated with powerful psychiatric drugs. Bipolar disorder involves sharp mood swings and affected children are sometimes very irritable or have explosive tantrums.

    —Eliminating the term "gender identity disorder." It has been used for children or adults who strongly believe that they were born the wrong gender. But many activists believe the condition isn't a disorder and say calling it one is stigmatizing. The term would be replaced with "gender dysphoria," which means emotional distress over one's gender. Supporters equated the change with removing homosexuality as a mental illness in the diagnostic manual, which happened decades ago.

    More from NBCNews.com health:

    Hey, guys, your beer gut could lead to a broken hip

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    This is your brain on exercise

     

    © 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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  • 20
    Jul
    2012
    2:06pm, EDT

    Mass murderers often not mentally ill, but seeking revenge, experts say

    By Maggie Fox, Senior Writer, NBC News

    Those who commit mass murders are often angry and isolated, but usually aren't mentally ill, violence experts said Friday after a shooting during the midnight screening of "The Dark Knight Rises" in an Aurora, Colo., movie theater. James Holmes was arrested as a suspect in the shooting that killed 12 people and wounded 59 others.

    “It takes a certain degree of clear-headedness to plan and execute a crime like this,” said James Alan Fox, a criminal justice professor at Northeastern University in Boston, who has written several books on mass murder and school violence.

    There are exceptions – Jared Loughner, who shot and killed six people in Arizona in 2011, gravely injuring then-member of Congress Gabrielle Giffords, was diagnosed with schizophrenia. Mental health experts say people with mental illness are not any more likely than anyone else to become violent, however.

    Mass murderers “often times feel that they are right and everybody else is wrong,” Fox said in a telephone interview. “They really tend to externalize blame, to see other people as responsible for their problems."

    They are often socially isolated. “They tend to be a failure at life,” Fox added.

    12 dead, 59 injured in Colorado movie theater shooting

    Such well-planned attacks are rare and not meant to make a statement, Fox said. “They basically want revenge,” he said.  “Contrary to the common misperception that these guys suddenly snap and go berserk, these are well-planned executions.”

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    The film the victims were watching is loaded with violence but it’s unlikely that actually inspired the attacker, Fox said. The film was opening that night and it’s doubtful the attacker was familiar with the script.

    “It was just coincidental, although it just made the situation more ambiguous for the people involved,” he said. Some of those who were in the theater said they initially first thought the shooting was part of the screening. 

    Early reports suggest Holmes did not have a police record and the University of Colorado has confirmed he was in the process of dropping out of a Ph.D. program in neuroscience there.

    Former FBI profiler Clint van Zandt  told TODAY that Holmes was almost certainly acting alone. “Today, so far, he appears to be … the lone wolf,” Van Zandt said. The attack was carefully planned, both Van Zandt and Fox said, which fits the patterns of such attackers.

    “They typically plan carefully how they are going to do it, where they are going to do it, what they are going to bring and what they are going to wear,” Fox said. In this case, the victims were not deliberately chosen, although the place, a packed movie theater, probably was.

    The attack may encourage copycat actions but not necessarily, Fox said. “What bothers me in situations like this is to see lists of the worst mass shootings,” he said. “It encourages people to try to break records.”

    Dr. Victor Schwartz, medical director of the Jed Foundation, which works to promote mental health among college students, agreed. “The media needs to be really careful in these situations,” he said. “On the one hand, you need to report the story. On the other hand, there is the danger of sensationalizing it, almost romanticizing the drama here.”

    Schwartz also advises resisting any attempts to speculate on whether violent videos or movies may have affected Holmes. “The research slants both ways,” he said. Some studies suggest that children who watch and play violent videos may become desensitized to some aspects of violence, but there is not a clear consensus.

    “None of these things is caused by a single factor,” Schwartz said. “Obviously, these are always very complicated events. The impulse is to find a simple explanation for complicated situations. It is important to resist it.”

    Experts say it’s almost impossible to predict attacks like this one. “Neighbors will come forward and say it was no surprise,” Fox said. “But it’s all after the fact. Beforehand, even though someone may fit a profile, we can’t predict they will do this sort of crime. It’s a very rare event and not predictable. That’s part of what makes it so scary.”

    Former FBI profiler Clint Van Zandt speaks with TODAY's Matt Lauer again, calling the Colorado movie theater shooter a "lone wolf," which he says is "the thing the FBI director and others are most worried about."

    Related content from NBCNews.com:

    • Theater shooter believed to be ex-graduate student at Colorado medical school
    • Police: 'Sophisticated' booby-trap in Colorado shooting suspect's apartment
    • Witnesses react online to 'Dark Knight' theater shooting

    229 comments

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  • 17
    Apr
    2012
    10:00am, EDT

    A blood test for depression? New research points the way

    By Linda Carroll

    A simple blood test may one day be all that’s needed to help parents figure out whether a child is suffering from clinical depression or normal teenage angst, a new study suggests.

    In a pilot study of 28 adolescents, scientists showed that teenage depression could be diagnosed through a panel of 11 genetic markers, according to a report published in the journal Translational Psychiatry.

    If the results are confirmed in larger trials, doctors may one day be able to screen for depression just as they do for diabetes, says study co-author Eva Redei, the David Lawrence Stein professor of psychiatric diseases affecting children and adolescents at Northwestern University's Feinberg School of Medicine.

    This new research could help not only teens, but also adults suffering from depression, says Dr. Michael Thase, a professor of psychiatry at the Perelman School of Medicine at the University of Pennsylvania.

    “This is very interesting early research that could point to the development of not just biomarkers, but also help with the identification of new genes that are involved with the expression of this common illness,” he says.  “And that could potentially lead to new treatments.”

    With no actual test, diagnosis of depression is currently subjective and depends on a person's ability to identify and describe symptoms. This is especially difficult for teens who may be particularly out of touch with what's going on.

    Researchers developed their test by first studying rats specially bred to model human depression. While rats don’t experience all the symptoms of depression, they do show many of the same signs.

    Related video: Does Facebook add to teen loneliness, depression?

    “They huddle together,” says Redei. “They don’t move around a lot. They aren’t much interested in playing. They’re less interested in food than normal rats. And they don’t sleep well.”

    Intriguingly, the "depressed" rats also respond well to certain antidepressants, says Redei. 

    "In reality, depression affects our ancient brains as much as our new brain,” she says. “And the ancient brain is the same in humans as it is in rats.”

    Severe depression is thought to be caused by a combination of environmental and complicated genetic factors, she explains, and given the right genetics, can be kicked off by “any kind of environmental challenge such as trauma or life stresses." 

    To see how the depressive brain reacts to environmental triggers, Redei and her colleagues looked at differences in the way normal rats and depression-model rats behaved in response to stress. They pulled blood samples from all the rats and found a host of markers that differed between the two groups.

    In the second part of their study, the researchers examined blood from 14 depressed and 14 healthy teens, looking at the levels of 26 markers that had been identified in the depression-model rats.

    They found that 11 of those markers, taken together, accurately predicted which teens were clinically depressed.

    Thase, of the University of Pennsylvania, says further research might be a boon to diagnosing both teen -- and adult -- depression.

    "Now you would want to see if they get the same results with older people," he says. "Or does it have something to do specifically with early onset depression?"

    TODAY's Ann Curry talks with author Lisa Earle McLeod and psychiatrist Dr. Janet Taylor about a new study that claims "supermoms," women who set the unattainable goal of being perfect, are more likely to suffer from depression. NBC's Kate Snow reports.

    63 comments

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Senior health writer for NBCNews.com. With 20 years experience reporting on health, science, medicine and technology, Maggie now specializes in writing health stories that the average reader can understand. Former global health and science editor, Reuters, who established an award-winning and agenda-setting science and health file for the news agency.

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Linda Carroll is a regular contributor to NBC News. She is co-author of the new book "The Concussion Crisis: Anatomy of a Silent Epidemic.”

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