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  • 1
    May
    2013
    12:02am, EDT

    Sneaky sugar: We're eating too much, and we don't even know it

    By Linda Carroll

    Americans may be heeding warnings to avoid sugary drinks, but many are still consuming way too much “added sugar” in their food, a new government report shows. 

    And most of those sugary foods are being consumed at home rather than at restaurants, said study co-author Bethene Ervin, a nutritional epidemiologist at the Centers for Disease Control and Prevention.

    Current government guidelines suggest that Americans limit total discretionary calories, including added sugars and solid fats, to 5 to 15 percent of food consumed per day. Ervin and her co-author Cynthia Ogden found that added sugars make up approximately 13 percent of the average American adult’s total intake.

    Ervin and Ogden found that adult consumption of added sugars declined with increasing income. So, while women in the lowest income category were consuming 15.7 percent of their calories as added sugars, those in the highest income category were consuming 11.6 percent of their calories as added sugars. The researchers found a similar trend for men.

    What surprised Ervin and Ogden was the lack of an income effect on kids. No matter what income bracket the kid came from, the consumption of added sugars was the same.

    “Income is often considered a proxy for education,” Ervin said. “So adults with more income and education may be making healthier lifestyle choices. But that may not be translating over for their children.

    ”One culprit is sugary sodas. Although other research has shown that soda consumption has been declining, if you look at individual foods and beverages, these drinks still lead the pack, Ervin said.

    Many Americans may not know how much total sugar they’re consuming because the sweeteners are often hidden in prepared foods, like ketchup, experts say.

    “I think people are interested in making changes and they’re heeding the warnings about sugary beverages,” said Sara Bleich, an associate professor of health policy at the Johns Hopkins School of Public Health. “But when it comes to food it’s much more complicated. Cereal, for example, has a tremendous amount of added sugar. And not everyone understands that breakfast foods like muffins and pastry, things that people don’t consider to be a desert or an indulgence, pack a lot of sugar.”

    Beyond that, there’s the issue of the tricky labeling found on food packages. “It takes 4 to 5 servings to fill a normal sized bowl,” Bleich said. “And that’s an enormous amount of sugar.”

    Sometimes it just comes down to convenience over health, Bleich said. “I don’t think that moms want to be buying a KFC meal every night, but there’s also no time for them to cook a three course meal,” she added.

    And then there’s the issue of dealing with kids who have absorbed all the marketing of sugary products. “It’s a two-way street,” Bleich said. “When it comes to kids, the whine factor does play a role.”

    If you’re wondering why all there’s all this fuss about sugar, Dr. David Heber is happy to explain.

    Too much added sugar, especially fructose, can lead to a multitude of chronic illnesses, said Heber, a professor of medicine at the University of California, Los Angeles, and director of the UCLA Center for Human Nutrition.

    We’re genetically engineered to consume fats and sweets because we evolved on the savannah where food was scarce, so you ate as much as you could when you could, Heber explained. But in times of plenty, we can wreak havoc on our bodies, he added.

    Fructose can convert to fat, which can not only make us heavier, but can also lead to a fatty liver – which is one of the leading causes of liver transplants, Heber said. Too much sugar can also lead to inflammation, which can raise the risk of heart disease.

    Part of the problem is the ubiquity of added sugars. “Breads, for example, have a lot of sugar,” Heber said. “It’s in all kinds of places you’re not expecting to find it, even foods like ketchup.”

    Heber suggests steering clear of processed foods. “You want a diet that his high in protein and low in fat with two thirds of your plate taken up by fruits and vegetables,” he said. 

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  • 25
    Feb
    2013
    9:25am, EST

    Tasty diet cuts heart disease, study finds

    By Maggie Fox, Senior Writer, NBC News

    A Mediterranean diet rich in fruits, vegetables, olive oil and a little wine can cut the risk of heart attacks and strokes by 30 percent, researchers reported on Monday in a study that shows the real-life benefits of a diet long encouraged by doctors.

    The results were so startling that the study was cut short after less than five years, and the results rushed to publication in the New England Journal of Medicine.

    “A Mediterranean diet supplemented with extra-virgin olive oil or nuts reduced the incidence of major cardiovascular events,” the researchers, led by Dr. Ramon Estruch of the Carlos III Health Institute in Barcelona, wrote.

    The study was done in Spain, where people already supposedly eat the Mediterranean diet -- which is characterized by lots of salad, fruit, vegetables, nuts, a little fish, a little lean meat, a small amount of cheese and olive oil.  Wine is also served at meals. But the 7,400 volunteers in the trial got extra counseling, and either a weekly supply of extra-virgin olive oil or mixed nuts.

    Many studies have shown that people who eat a Mediterranean diet are less likely to die of heart disease. This one was powerful because it randomly assigned people to eat such a diet as part of their normal lives over several years.

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    The 7,400 patients aged 55 to 80 were all high risk of heart disease because of diabetes, a family history of heart disease, high blood pressure, unhealthy cholesterol levels or they were overweight or smokers.

    They were randomly assigned to one of three groups: a Mediterranean diet with extra-virgin olive oil added; the same diet but with mixed nuts; or just a standard diet with advice to cut fat. They were given either a liter of olive oil per week (for the olive oil group), 30 grams of walnuts, hazelnuts and almonds (for the nut group), or little non-food presents for the control group.

    They all got individual and group counseling.

    After nearly five years, 58 people who simply followed a low-fat diet had strokes, but just 32 people did if they ate a Mediterranean diet with nuts, and 49 who followed the Mediterranean diet with extra olive oil. The Mediterranean diet also cut the risk of heart attack.

    Thirty people died from heart disease in the control group, compared to 31 who ate the Mediterranean diet with nuts and 26 who at the Mediterranean diet with olive oil.

    But the people who ate a Mediterranean diet were less likely to die overall in the five years, compared to those in the control group. Overall, the Mediterranean diets cut the risk of heart disease death, heart attacks and strokes by 30 percent, the researchers calculated.

    "This is another piece of evidence for the benefits of diets containing 'good' fats such as those in olive oil and nuts," said nutrition expert Marion Nestle of New York University. 

    "I wonder whether they plan to continue the trial for a longer time—I didn’t see any comment on that—because a few more years might give greater clarity," Nestle added in an e-mail.

    There are lots of reasons why a Mediterranean-style diet might reduce heart disease. Researchers had noticed that people in Northern Europe, who eat butter and lard more than olive oil, were more likely to die of heart disease than their Southern European neighbors, even if they were just as overweight and exercised the same amount.  A study of the diet’s benefits published back in the 1960s showed the diet cut the rate of strokes and heart attacks, probably because it lowered cholesterol levels.

    Olive oil and nuts contain monounsaturated fats, which are better for artery health than the saturated fats found in butter, meat and lard. The diet is also high in fiber and vitamins such as A, C and E, as well as minerals.  Walnuts and fish are rich in omega-3 fatty acids, which have been shown to benefit heart health. And reducing meat has been shown to cut the risk of both heart disease and cancer.

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  • 19
    Oct
    2012
    12:50pm, EDT

    To fight obesity, WHO agency partners with sugary drink, salty snack makers

    Shannon Stapleton / Reuters

    Coca-Cola, Nestle and Unilever, all manufacturers of the type of food and soft drink products that nutrition experts say help cause obesity, are contributing to the Pan American Health Organization's effort to combat the epidemic in Mexico. But are they undercutting the organization's efforts?

    By Duff Wilson and Adam Kerlin, Reuters

    GENEVA, Switzerland -- As the world's foremost health agency, the World Health Organization bills itself as an impartial advocate working on behalf of 194 member nations.

    Its mission as the public health arm of the United Nations ranges from stanching communicable diseases such as malaria and AIDS to battling what the U.N. considers the latest "global epidemic": chronic ailments such as diabetes and heart disease caused primarily by unhealthy diets.


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    But to fight those diseases in Mexico, the nation with the world's highest rate of obese and overweight adults, a Reuters investigation found that WHO's regional office has turned to the very companies whose sugary drinks and salty foods are linked to many of the maladies it's trying to prevent.


    The office, the Pan American Health Organization, not only is relying on the food and beverage industry for advice on how to fight obesity. For the first time in its 110-year history, it has taken hundreds of thousands of dollars in money from the industry.

    Accepting industry funding goes against WHO's worldwide policies. Its Geneva headquarters and five other regional offices have been prohibited from accepting money from the food and soda industries, among others. "If such conflicts of interest were perceived to exist, or actually existed, this would jeopardize WHO's ability to set globally recognized and respected standards and guidelines," said spokesman Gregory Härtl.

    But the Pan American office -- known as PAHO, based in Washington and founded 46 years before it was affiliated with WHO in 1948 -- had different standards allowing the business donations.

    Even so, not until this February did PAHO begin taking industry money, Reuters found: $50,000 from Coca-Cola, the world's largest beverage company; $150,000 from Nestle, the world's largest food company; and $150,000 from Unilever, a British-Dutch food conglomerate whose brands include Ben & Jerry's ice cream and Popsicles.

    The recent infusion of corporate cash is the most pointed example to date of how WHO is approaching its battle against chronic disease. Increasingly, it is relying on what it calls "partnerships" with industry, opting to enter into alliances with food and beverage companies rather than maintain strict neutrality. The strategy differs dramatically from WHO's approach to interacting with the tobacco industry - companies with which it is unwilling to partner.

    The decision appears to stem in part from necessity.

    Despite being tasked a year ago by the U.N. to direct the attack on what both groups now call a "global epidemic," WHO has cut its own funding for chronic disease programs by 20 percent since 2010 -- an even bigger decline than for the agency as a whole. These diseases cause 63 percent of premature deaths worldwide, but the WHO department that leads the effort to fight them receives 6 percent of the agency's budget.

    The industry's cash donations, which have not been previously reported, were described by Irene Klinger, a senior adviser for partnerships in PAHO, as "a new way of doing business." She compared the closer cooperation with that of a couple who needs to discuss marital problems. She said PAHO spends about $30 million a year to fight chronic diseases. But amid WHO's budget cuts, Klinger said, the organization needed industry "money to make this happen."

    Mexicans drink far more Coke than citizens of any other nation. But even as Coca-Cola denies that soda causes obesity, it says it is committed to solving the health crisis. The Atlanta-based company has placed a top official on the steering board for WHO's Pan American Forum for Action on Non-Communicable Diseases, a group that helps determine how WHO fights obesity in Mexico.

    Klinger and other WHO officials who work with industry say they are careful to maintain control of policymaking. But on its website, the Pan American Forum touts the benefits of membership as helping businesses "avoid regulation" and "influence regulatory environments."

    "WHO is getting hijacked," said Boyd Swinburn, an Australian professor and longtime member of WHO's nutrition advisory committees. "They're cash-strapped, and they're bringing the private sector in. That's very dangerous."

    Coke sees the situation differently.

    "It's about the convergence of the interests," said Jorge Casimiro, Coca-Cola's director of international government relations and public affairs. "What we're trying to say is we're ready to take action. We're companies who want to do this. We're ready to go."

    Ties to industry
    As part of its investigation into the influence of Big Food on WHO, Reuters reviewed thousands of pages of records, and interviewed more than a hundred experts and officials from industry, academia, health groups, trade groups, medical journals and national governments. Among those interviewed: more than 20 former and current WHO officials and leading advisers to the agency.

    Although WHO wields no official regulatory authority, the agency relies on member nations to embrace its recommendations -- something that happens quite often in developing nations. "The standards and policies adopted by WHO basically become the laws and regulations and policies in many of these countries," said Daniel Spiegel, a former U.S. ambassador to U.N. programs in Geneva who now lobbies on behalf of the food and alcohol industries.

    Reuters found that even when WHO takes special care to avoid entanglements with industry, the wall meant to protect WHO's impartiality is far from impermeable.

    A small group at WHO headquarters here is helping a panel of nutrition experts draft new guidelines for sugar, salt and fat in the diet. Little known to the public, the guidelines are of intense concern to potentially affected companies, and they're particularly relevant to developing nations such as Mexico.

    The Nutrition Guidance Expert Advisory Group was hand-picked by WHO staff members, who say they took the agency's strictest steps yet to avoid the industry conflicts of some advisers in the past.

    "My main message is we're really taking this conflict of interest extremely seriously, as well as the solidity of the science, and we're trying to really change this perception," said Francesco Branca, director of the work.

    Reuters found at least two of the 15 advisers had direct financial ties to the food industry. Murray Skeaff, a New Zealand professor, received research money from Unilever, the conglomerate with $60 billion sales last year. He could not be reached for comment. Esté Vorster, a South African professor, advised a sugar association and took travel and "after hours" money to judge a contest for Nestle. Vorster said she does not participate in discussing the sugar guideline.

    A third, Nahla Hwalla, is a professor and dean of a food-sciences college at the American University of Beirut. The college is receiving $750,000 over three years from Nestle; $450,000 of that money goes to fund the work of a doctoral student whom Hwalla is supervising. Hwalla said the Nestle funding was disclosed to WHO. WHO will not comment on financial disclosures by members of its advisory group.

    In addition, three members of the group -- Ibrahim Elmadfa of the University of Vienna, Anna Lartey of the University of Ghana, and Vorster -- are current, future or past leaders of a professional society, the International Union of Nutritional Sciences. The society solicits hundreds of thousands of dollars in industry funding for conferences.

    Sponsors of next year's conference include Coca-Cola, PepsiCo, Kraft, Nestle and Unilever. A letter to sponsors from Angel Gil, a Spanish professor and conference president, says sponsors would "enjoy prime exposure and direct marketing opportunities with the key players and decision makers in the field."

    The conference organizers advising WHO say they do not regard the ties as a conflict of interest because they don't pocket any of the money personally.

    But the conference they lead has so many ties to industry that WHO itself will no longer help organize or donate money to it as it has done in the past, according to Chizuru Nishida, coordinator of the WHO nutrition policy and scientific advice unit.

    Influence in Mexico
    The industry's influence in Mexico is exemplified in the Mexican delegations to a group called Codex. The group works with WHO on food labeling and trade policies, and its guidelines serve as a reference for governments around the world.

    At a meeting of the group's nutrition committee last November in Germany, the five-member Mexican delegation included officials from Coca-Cola and Kellogg -- but no one from the Mexican government. Many other nations also invited company representatives; a Coke official was part of the U.S. delegation. But all delegations except Mexico's were led by government officials.

    Coca-Cola is a major player in Mexican politics, and dominates the soda market there. Vicente Fox, the nation's president from 2000 to 2006, was the president of Coca-Cola Mexico before entering politics.

    Coke points to its contributions to public health. "Close to 26 million Mexicans benefit from the more than 4,000 sporting events we promote each year," said Rosalyn Kennedy, senior communications manager for Coca-Cola. In an email, she said Coke also signed the National Agreement to Prevent Obesity with the Mexican government. As part of the agreement, companies promise to reduce salt, sugar and fat and promote exercise and drinking water.

    Swinburn, who directs the WHO Collaborating Centre for Obesity Prevention in Melbourne, remains skeptical of the industry's motives. He said food and beverage companies exert a huge influence on policies that affect the health of millions.

    "Industry is buzzing all around," he said. "Even in things like nutrition guidelines, they're usually in the room at the policymaking table or buzzing around it and putting all sort of pressure on, bringing their huge conflicts of interest and their huge resources to it - and we're wondering why we don't get much public interest policy coming out."

    In May 2011, an expert group impaneled by PAHO, WHO's regional office for the Americas, wrote perhaps the world's toughest plan to restrict junk-food marketing to children. The panel, including four Mexicans, recommended new government policies "in a time frame of no more than 18 months" -- that is, by November 2012.

    To date, Mexico has yet to act on the findings. PAHO has yet to even formally present its report to the Mexican government, according to Alejandro Calvillo, a member of the expert panel and director of El Poder del Consumidor, or Consumer Power, a nonprofit group focused on obesity in Mexico.

    Why not? Calvillo said public health officials with PAHO in Mexico "do not want to have any kind of conflict with the industry."

    The view wasn't disputed by Enrique Jacoby, PAHO's regional adviser on healthy eating. "We have an opportunity to do more than we did in the past with Mexico, I'll put it that way," Jacoby said.

    "We cannot act on our own," Jacoby said, "but in reality we can have a huge influence on Mexico insofar as the secretary of health in Mexico says, 'PAHO, come over and help us do this,' because we are the international health agency."

    Some WHO officials and health advocates say the agency is doing the best it can -- with industry help -- to reduce chronic disease. The World Health Assembly in May set a target for a 25 percent reduction in global deaths from these illnesses by 2025.

    "To do that, you have to reduce salt, reduce sugar, reduce fats; that's not going to happen without regulation and taxation," said Judith Watt, interim director of an alliance of global diabetes, heart, cancer and lung disease groups, which receive some industry funding.

    WHO has repeatedly advocated for voluntary action over stronger, regulatory measures. And the major food makers have, in some cases, responded.

    For instance, Coca-Cola now offers more than 800 no- or low-calorie drinks; the Mexican bakery giant Grupo Bimbo is cutting sodium in its leading bread and rolls; and Nestle and General Mills just announced further cuts by 2015 in the sugar and salt in Cheerios and other cereals. Further, these companies are promising to limit advertising aimed at children under 12.

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    WHO published global guidelines for controlling junk-food marketing to children in 2010. It suggested "industry-led self-regulation" as an alternative to legal requirements.

    Corinna Hawkes, a British food policy expert and lead author of a seminal 2004 WHO report on marketing of food to children, said self-regulation alone continues to fall short, in Mexico and elsewhere. She was part of the panel PAHO convened last year to recommend what it called "concrete" policies.

    Their report advocated restricting all forms of junk-food marketing that appeals to children under the age of 16. That included TV, radio, signs, cartoons, toy giveaways and event sponsorships, a Coke mainstay in Mexico. Further, it said governments should raise taxes on products high in sugar, fat and salt and on the advertising of these products -- policies anathema not only to fast-food and soda companies but to many in advertising and media.

    Since then, Hawkes said, neither WHO, PAHO nor the Mexican government has done much.

    In a speech last year in Mexico City, Margaret Chan, WHO director-general since 2007, talked about "the seductive marketing of foods and beverages that are cheap, convenient, tasty, filling, and very bad for health." But Chan didn't mention the solution being proposed by WHO's expert committee. She declined interview requests for this story.

    Mexican President Felipe Calderón also championed a five-step anti-obesity program focused on exercise and healthy eating. He, too, didn't mention limiting marketing to children.

    Calderón had appeared with Coca-Cola chief executive Muhtar Kent at the World Economic Forum in Davos, Switzerland, in January. Kent said Coke would invest another $1 billion a year to grow the Mexican market. Calderón praised the plan for adding jobs.

    Coke has plans to double its sales in Mexico within a decade.

    ‘Recipe for disaster’
    Mexican Coke is made with real cane sugar instead of corn syrup. And Mexicans love it.

    So much so, they drink an average of 45 gallons of Coca-Cola products a year. That's almost eight times more than the world average and 70 percent more than Americans, who are the second biggest soda drinkers in the world.

    "A recipe for disaster," said Kelly Brownell, director of Yale University's Rudd Center for Food Policy and Obesity.

    Body measurements bear him out: Mexico now has the fattest adult population in the world, surpassing the United States in the latest surveys measuring body mass index, excluding some small South Seas Islands.

    Studies show 69.5 percent of Mexicans 15 and older were overweight or obese in 2006 compared with 69.2 percent of similarly aged Americans in 2010. And Mexico's problem continues to grow while the situation in the United States has leveled out, health officials say.

    A new survey is expected to show Mexico's obesity rates climbing about 2 percent since 2006, according to Simón Barquera, a professor of nutrition and researcher in the National Institute of Public Health.

    "This is as high as you could get," Barquera said.

    In its one significant government response, Mexico in 2010 began removing sugary drinks from elementary schools. But school children still lack water fountains, and soda marketing pervades the places they gather. The national government has rejected proposals to tax sugary drinks.

    Nestle funds diabetes group
    The food industry's influence is by no means limited to Geneva or Mexico. A Reuters investigation earlier this year revealed how food and beverage companies now dominate policymaking in Washington and in cities and states across America.

    In Washington, the companies doubled their lobbying expenditures to $175 million during the first three years of the Obama administration, Reuters found, and defeated "soda tax" proposals in 24 states. As part of the National School Lunch Program, Congress even declared pizza a vegetable.

    Food and beverage companies also are donating money to global nonprofit groups fighting the very diseases that their products have helped to create -- health advocacy organizations that are allowed to work with officials at WHO headquarters in ways that industry groups cannot.

    In a precedent-setting move earlier this year, Nestle agreed to give 480,000 euros ($630,000) to the International Diabetes Federation over three years. The amount of the donation, provided to Reuters by Nestle, has not been previously reported. The federation previously took money from insulin makers but not food companies.

    "We want to be part of the solution," said Robin Tickle, Nestle's head of corporate media relations. "We have various forms of partnerships with organizations all over the world at global, regional or local level. Some of these involve donations, others do not."

    Ten of the largest multinational companies have joined forces in a nonprofit group in Geneva called the International Food and Beverage Alliance. The companies, with combined sales last year of $397 billion, are promising voluntary actions to reduce salt, sugar and fat. Their group, created four years ago, is trying to gain a status of "official relations" with WHO, which would give it additional access to agency meetings and shared work plans.

    The global sugar industry, with U.S. government backing, reacted strongly against a WHO expert panel's report in 2003 to recommend limiting sugar to 10 percent of dietary calories. Since then, the report has not been mentioned in WHO's plans to fight chronic disease, and some of its most aggressive staff members have left the organization.

    "Many of us have been complaining to Margaret Chan about why there are so few staff on this even if it is two-thirds of the mortality in the world," said Pekka Puska, WHO's director of non-communicable disease until 2003 and currently director general of Finland's National Institute for Health and Welfare.

    "You can speculate why," Puska said. "The more you do non-communicable diseases, the more you run into commercial problems of marketed products like Coca-Cola."

    Giants including Coke and Unilever take exception to such characterizations. "It's about working together," said Anne Heughan, external affairs director for Unilever. She said all such efforts to battle obesity and other diseases need "to be led by the government. They need to set the direction ... But obviously we are a part of that."

    Focus on salt
    The soda industry still disputes whether sugar causes obesity and its cavalcade of health problems. The underlying cause of obesity is consuming too many calories and burning too few. The industry argues that a calorie from soda is no different from a calorie from any other source.

    Many health experts compare that argument to the longtime denial by tobacco makers that cigarettes cause cancer. Cause and effect has not yet been biologically established for soda and obesity. But sodas are the leading single source of calories in the American and Mexican diets. And they are "empty" calories -- devoid of nutritional value.

    There is no such dispute over the harms of excess salt -- nor is the industry lobby as focused. Companies that add salt to food have agreed it can cause hypertension.

    Accordingly, salt remains a target of WHO disease policies even as sugar has fallen off the table. The industry-funded Pan American group is focusing on salt reduction. An outline of policy options by WHO in March listed salt 28 times and sugar only once.

    Spending cuts
    Since the industry's business alliance formed in Geneva in 2008, WHO has cut its annual spending for the branch dealing with chronic disease. Its budget went from $325 million for 2008-09 to $241 million for 2012-13; in the same period, the office's staff shrank from 182 to 131.

    Chan's 2012-13 budget reflects more of the austerity that forced the agency to cut 250 staff members agency-wide last year. The budget, emphasizing "efficiencies" and "partnerships," is 12 percent smaller overall -- but 20 percent smaller in the chronic disease office than the previous spending plan.

    WHO's entire budget is about half of what Coca-Cola spends on marketing alone. Although WHO spends about $2 billion a year and employs 8,000 people to fight disease, the vast majority of that money is earmarked by donors for projects related to communicable diseases such as malaria. That leaves relative crumbs for the diet-related illnesses that WHO says are the world's leading killers.

    "Sixty-three percent of the deaths, and 5 (to) 8 percent of our budget," said Douglas Bettcher, acting director of the chronic diseases office. In an interview here, Bettcher described the handful of people at policy levels: "We've got one person on diabetes, two on cancer, one on cardiovascular disease, and we're recruiting one for chronic respiratory disease," he said.

    That alone doesn't represent the entirety of WHO's effort. Bettcher said many other WHO employees are working on the risk factors of chronic disease (including smoking) around the world. Among them: about 200 technical officers. He said he remains positive about the potential to make progress.

    "I'm optimistic we're well on our way to scaling up our efforts," Bettcher said.

    Some of WHO's own employees, however, acknowledge the difficulties.

    "Money has been cut back," Nishida said. "Today it seems like the only people that have money are industry."

    Derek Yach, a former WHO assistant-director-general for chronic disease programs, said "WHO is really pushed into a corner" by its budget woes. Yach said he was driven out of WHO in 2005 after proposing to limit sugar consumption. Not long after, he made a dramatic career move that underscores just how ineffective he believes WHO has become.

    After stints at Yale and the Rockefeller Foundation, Yach accepted a job as a vice president at PepsiCo. His reasoning: He said he thought he stood a better chance of improving public health by working for the sugary soft drink maker than by working for the world's leading health organization.

    Shared interests
    Under Chan, WHO has employed "partnership advisers" to seek closer relationships with food and beverage companies. One of them, Janet Voûte, left the health agency in 2010 to become a vice president at Nestle, which is based in Vevey, Switzerland -- two train stops from Geneva.

    Nestle, Voûte said, agrees with everything WHO is doing and stands ready to help WHO and improve its own products. "I personally do not see any major conflict of interest," she said. "I see much more convergence of interests."

    When WHO held a conference for health ministers last year in Moscow - which Voûte had helped to organize -- one session was chaired by Casimiro, the top Coca-Cola official. He said he was invited by WHO to chair it.

    Speakers came from PepsiCo, Nestle and the World Federation of Advertisers. They called for voluntary action and offered their resources and influence.

    When Chan spoke, praising them, an activist stood up and asked Chan about whether the relationship posed a conflict of interest for WHO.

    Chan responded in her sometimes ebullient fashion.

    She sang the opening lines of a show tune from the musical The King and I: "Getting to Know You."

    Additional reporting by Stephanie Nebehay in Geneva.

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  • 28
    Aug
    2012
    8:02am, EDT

    Weight gain won't budge after menopause? Study offers diet strategies

    Courtesy of Robin Herman

    Robin Herman, 60, says it's harder to keep weight off after menopause. But some simple, subtle changes may help.

    By Maggie Fox, Senior Writer, NBC News

    Robin Herman has always been slender. She eats right, exercises regularly and keeps an eye on her weight. But middle age and menopause have hit her right in the waistband, and she’s frustrated.

    “What is this? I used to be able to look straight down at my feet and now there’s this rounded tummy in the way,” Herman says. While she’s still not overweight, Herman, 60, has gained 11 pounds that she just can’t seem to shake. Her problem illustrates what many women are finding in mid-life -- they are putting on pounds despite their best efforts.

    “At first I cut back about a quarter of what I was eating. And then I was just eating about half of what I had been eating. Now I don’t take seconds. I don’t eat a lot of bread. I don’t eat potatoes. I don’t eat empty calories. I don’t drink sodas,” said Herman, who recently retired from the Harvard School of Public Health in Boston.

    She joined Weight Watchers, a program that’s been clinically proven to work in helping people lose weight. “I kept a food diary. You could eat as many fruits and vegetables as you wanted. I put in a little more exercise,” she says.

    “I got nowhere. It just wasn’t doing anything. And it was making me crazy about following every spoonful I ate.”

    Herman sounds like thousands of women across the country who are slowly tipping over the point from being normal weight to overweight, or from being overweight to obese. A study published on Tuesday sheds a little light on what may work and why some approaches that help women shed a few pounds in the short term aren’t helping them keep the weight off long-term.

    Bethany Barone Gibbs of the University of Pittsburgh Medical Center and colleagues analyzed data from a study of more than 500 overweight women in their 50s and 60s to see what made a difference. They had been randomly assigned to either intensive nutritional and exercise counseling, or to a more general, less weight-loss-focused program. The woman also reported what and where they ate, for four years.

    As expected, more of the women who got specific diet and nutrition counseling lost weight. But Gibbs and colleagues wanted to know what worked for any of the women who managed to lose weight, regardless of which group they were in.

    Early on, some of the more obvious diet strategies worked -- eating less fried food, staying away from restaurants, avoiding sweets and eating more fish. But these approaches didn’t work for the women in the long term, Gibbs reported in the Journal of the Academy of Nutrition and Dietetics.

     “What we found at four years is that the women who changed their eating behaviors to eat more fruits and vegetables, who ate less desserts, less sugar-sweetened beverages and less meats and cheeses were more likely to have greater weight loss or less weight gain long term,” says Gibbs, an assistant professor in the Department of Health and Physical Activity.

    “But on the other hand, something like eating more fruits and vegetables did not predict weight change at six months but was one of the most important predictors for long-term weight change.”

    Avoiding restaurants didn’t seem to make a difference long-term, either, she said. Gibbs said the key to keeping weight off long-term may be a little counter-intuitive. “Short term, people are still motivated when they start a weight loss program,” she said. “They are never going to eat another French fry, eat another piece of pie, so you see the pounds coming off.”

    But hardly anyone can keep this kind of abstinent behavior up forever. The women who added fruits and vegetable to their diets, using them to replace higher-calorie meats and cheeses, lost more weight over the long-term. “That small change can give you a big, long-term result,” Gibbs said.

    How could something so subtle work better than going for the big effect? In part, it’s because weight gain is often subtle and sneaky, too, says Katherine Tallmadge, a personalized nutrition counselor and speaker and immediate past president of the DC Metro Area Dietetic Association. “When people gain weight, it’s usually a pound or a pound and a half a year,” she says. “It is a very small and creeping kind of weight gain.”

    The study also illustrates what many middle-aged women complain about. “I recall at age 25 if I wanted to lose five pounds I could do it in a week.  Now, it takes far longer to lose weight,” says Karen Giblin, president of menopause support organization Red Hot Mamas North America, Inc.   

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    This doesn’t surprise Dr . Domenica Rubino, an endocrinologist who runs the Washington Center for Weight Management and Research. “As we age, the average person has a tendency to gain weight and to gain more fat than muscle,” Rubino says. On top of this, women are undergoing hormonal changes that can disrupt sleep, stress them out and make them tired, three things also associated with weight gain. “Women are getting early morning awakening  and even though they are exhausted, they are not getting back to sleep,” she says.

    Giblin can vouch for what happens next. “My willpower goes down the tube when I'm stressed and I will not do all the good things I should do be doing like eating properly and exercising,” Giblin says.

    It all can add up to the muffin top effect: that shift of weight to the abdomen that makes clothes fit poorly, if at all, and that stresses out a woman every time she gets dressed.

    “It’s so hard counting calories and keeping food diaries for years and years and years,” Gibbs agreed. “We have a population-sized problem here.” With two-thirds of Americans overweight or obese, she says, people need some simple solutions.  

    “I've had to make exercise a lifestyle choice,” says Giblin, who co-authored "Eat to Defeat Menopause" with Dr. Mache Seibel last year. “Never skip a meal,” she advises. “And if you are prone to snacking, grab a piece of fruit or six  to eight almonds.”

    Rubino says hormone replacement therapy can help, too, if it helps cut hot flashes and anxiety. “You are sleeping better and not having the hot flashes and your mood is better,” she says.

    STOP Obesity Alliance Director Dr. Scott Kahan says managing stress can really help people control weight. “If things are very stressful, things are going on in your life, often stress management techniques can help,” he says.

    Kahan and others admit this can be easier said than done. “I think we live in a very difficult time, a toxically busy world,” Tallmadge says. “What really upsets me is when people call themselves lazy or undisciplined when in fact they are running themselves ragged.”

    But it’s not exercise.  Many women are busy getting their families ready for the day and then commuting during the very morning hours when they would have been otherwise most likely to exercise.

    “It’s a real balancing act.”

    Related stories:

    • Weight worries after 50
    • How to lose that matronly look after menopause
    • Stroke rates triple among middle-aged women

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  • 19
    Jul
    2012
    10:51am, EDT

    Why you won't be getting the new diet drugs any time soon

    FDA

    The Food and Drug Administration has approved two new diet drugs, but both have restrictions about who can -- or should -- take them.

    By Maggie Fox, Senior Writer, NBC News

    The Food and Drug Administration has approved two new diet pills in a week -- the first new obesity drugs to be approved in 13 years. The agency, usually dry about its approvals, practically gushed about the pent-up demand for new obesity treatments in a country where more than two-thirds of the population is overweight or obese and steadily getting fatter.

    “These prescription medications would be taken for the rest of a person’s life,” the FDA says on its website. 

    “For many people, obesity is a life-long condition, but we don’t always think of it -- or treat it -- as such,” said Dr. Amy Egan, deputy director for safety in FDA’s Division of Metabolism and Endocrinology Products

    But don’t expect to be able to get either drug easily. Each of the new drugs -- Belviq and Qsymia -- is being restricted in a different way. And consumer advocates say dieters should think twice about taking either.

    The FDA was so worried about Belviq, approved last week, that it has asked for the Drug Enforcement Administration to control its use, like it does opiate painkillers. The DEA must now decide what restrictions to put on the pills, a process Belviq’s maker, Arena, says could take several months.

    Qsymia, approved on Tuesday, won’t have these restrictions. But the FDA and drugmaker Vivus have worked out a plan to try to ensure that doctors don’t start running diet pill-mills.

    “The only way the doctors will be able to prescribe Qsymia is through a certified pharmacy,” Vivus vice president Dr. Barbara Troupin said in an interview. That means they won’t be able to stock it themselves -- and they’ll be barraged with educational materials, Troupin said.

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    Vivus will track which doctors are prescribing the drug, and which ones undergo training. “If a prescriber wants to write for (prescribe) the drug, they can write for the drug. But we will have their information and continue to inform them about the risks and who the appropriate patients are,” Troupin said. “Hopefully, they won’t view it as being tormented.”

    But the FDA and Vivus understand that people are likely to be clamoring for the drug, and there are clear guidelines on who should take it. Women who might get pregnant shouldn’t, for one -- the drug causes birth defects including cleft palates. Nor should people with overactive thyroids or who have heart disease risks such as an irregular heartbeat.

    Approved patients should be obese, meaning they have a body mass index -- a measure of height to weight -- of 30 or greater. The National Institutes of Health has a BMI calculator here. A person 5 feet 5 inches tall is considered overweight at 150 pounds and obese at 180 pounds. People with BMIs of 27 may be eligible if they have a weight-related condition such as high cholesterol.

    Doctors will be asked to monitor patients closely, watching heart function and looking for signs that a patient may become suicidal --a side effect of drugs related to topiramate, the seizure drug included in the two-drug Qsymia cocktail.

    These precautions do not satisfy Dr. Sid Wolfe of Public Citizen, who has campaigned against Qsymia and Belviq.

    “I would be very surprised if either of these drugs stays on the market very long,” Wolfe said in an interview.

    Food and Drug Administration officials approved the diet drug Qysmia this week.

    He points to the long list of withdrawn diet drugs, from Dexatrim, which caused fatal strokes, to fenfluramine, withdrawn in 1997 because it could damage heart valves, and ephedra, banned in 2004 after it was found to cause deadly heart attacks, strokes and other ills. Wolfe was disappointed when Qsymia won approval.

    “There are a bunch of problems with it,” he said. “One is there is not remotely any kind of failsafe way to keep pregnant women from using this drug.”

    Americans and drug companies are looking for an easy way out, but study after study shows good, old-fashioned careful eating and exercise works better than any diet pill, Wolfe says. And healthy eating and exercise have the added bonus of lowering the risk of heart disease, cancer, diabetes, arthritis and even Alzheimer’s disease. Wolfe's group approves of carefully designed programs that help people do that.

    “People are just so desperate to approve something because they haven’t done anything for 13 years,” Wolfe said. One of Qsymia’s components, phentermine, is on the market as a diet drug. The only other diet drug on the market is orlistat, which stops the body from absorbing fat. A low-dose version, Alli, is even available without a prescription. But that’s it. The only other option for severely obese people, besides diet and exercise, is surgery to limit how much they can eat.

    It is possible to get a home-made version of Qsymia. Any licensed doctor can prescribe phentermine together with certain versions of topiramate, the epilepsy drug, although the FDA doesn’t recommend it.

    Related stories:

    • FDA approves new weight loss drug
    • FDA approves first new weight loss drug in 13 years
    • Craving a safe diet drug

     

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  • 17
    Jul
    2012
    7:52pm, EDT

    FDA approves weight-loss drug, with a new name - Qsymia

    By Maggie Fox, Senior Writer, NBC News

    The U.S. Food and Drug Administration approved the new weight loss pill Qsymia on Tuesday, adding to a very skimpy arsenal of drugs Americans can take to battle severe obesity -- and adding a last-minute name change after two years of wrangling over whether to approve the drug.

    Qsymia  (pronounced kew-SIM-ee-ah) pairs an old stimulant drug with an epilepsy drug to try and bring some options to the two-thirds of Americans who are overweight or obese -- and who have higher rates of heart disease, diabetes, stroke and cancer as a result.

    “Obesity threatens the overall wellbeing of patients and is a major public health concern,” Dr. Janet Woodcock, director of the FDA’s Center for Drug Evaluation and Research, said in a statement. “Qsymia, used responsibly in combination with a healthy lifestyle that includes a reduced-calorie diet and exercise, provides another treatment option for chronic weight management in Americans who are obese or are overweight and have at least one weight-related comorbid condition.”

    It’s the second obesity drug to win FDA approval this summer. Last month, the agency OK'd Belviq, the first new weight loss drug approved in 13 years. Qsymia combines phentermine, a stimulant, with the anti-seizure drug topiramate.

    The FDA took its time in reviewing Qsymia, formerly known as Qnexa, because of fears about the side-effects, which can include a fast heart rate and metabolic acidosis, a condition marked by highly acidic blood that can, in severe cases, put people into a coma and even kill them. Metabolic acidosis can also cause kidney stones and damage bones. There’s been a growing debate over whether it’s worth the risk of taking drugs that could damage the heart to battle the growing obesity epidemic.

    Diet drugs have a sketchy history in the U.S. and the FDA worries about irresponsible doctors who dispense pills from their offices to just about all comers, whether they’re in the group that’s supposed to get the drug or not. The FDA approves drugs for certain uses in certain people, but once a drug is approved, a licensed doctor may prescribe it as he or she sees fit.

    Vivus, the company that makes the drug, has said it’s aware of this and has said it would restrict who can prescribe Qsymia and how. The once-a-day pill will be available only through mail order so that doctors cannot dispense it from their offices. The company also plans to educate doctors about the drug's risks, which include birth defects, and to carefully watch users for any signs of heart damage.

    The agency asked for a last-minute name change from Qnexa, however. "The FDA indicated concern about potential confusion regarding the name Qnexa and worked with Vivus during the final steps of the review process to identify Qsymia as an acceptable brand name," Vivus's Dr. Barbara Troupin said in a statement.

    Qsymia is approved for use in obese adults, those with a body mass index of 30 or greater, and overweight adults, those with BMI of 27 or greater, who have at least one weight-related condition such as high-blood pressure, type 2 diabetes or high cholesterol. 

    This doesn’t calm the fears of Dr. Michael Lauer, a cardiologist at the National Institutes of Health who was on the panel of experts that advised the FDA about the drug.  Lauer and one other panelist voted against approval, but 20 panelists endorsed the drug in February.

    "I believe that if the public were to 'buy' (Qsymia) after FDA approval, it would run the risk of severe, even fatal, consequences from another diet lemon," Lauer writes in Tuesday's issue of the Annals of Internal Medicine.

    “If we think about the history of obesity medications, we've seen plenty of lemons. Ephedra, fen-phen, phenylpropanolamine, and sibutramine had to be withdrawn from the market because of cardiovascular toxicity. Rimonabant was approved for sale in Europe, but was never approved in the United States because of severe psychiatric side effects,” he added.

    Lauer is not the only opponent. Public Citizen, a consumer group, has been campaigning against the drug, too.

    "As was the case for the diet drug lorcaserin (Belviq), approved last month despite concerns about heart valve damage, it was also reckless of the Food and Drug Administration to approve Qnexa. Research shows the medication increases heart rate, and four patients on the diet pill had non-fatal heart attacks during the clinical trials, while none of those on the placebo had heart attacks," Public Citizen's Dr. Sidney Wolfe said in a statement.

    "It is magical and delusional thinking for anyone to believe that a drug will turn off hunger without hitting other targets where it will do harm, usually to the cardiovascular system."

    Vivus hopes it will be a safer successor to the notorious and now banned “fen-phen” diet cocktail. Fen-phen combined fenfluramine and phentermine -- one of the two drugs in Qsymia -- but it damaged the heart in some cases and caused a condition in some patients called pulmonary hypertension, which causes fluid to build up in the chest, bringing a feeling of breathlessness.

    Reviewers say the amount of the drug phentermine in Qsymia is safer. The two drugs together seem to lower appetite while keeping patients perky. Lauer said he would have liked to see more tests to specifically look for heart problems before the FDA approves the drug.

    Doctors tested the pill in more than 4,430 overweight and obese patients. About half lost 10 percent  of their weight -- enough to lower cholesterol and blood pressure, reduce the risk of diabetes and early death.

    The drug, which suppresses appetite, is available to severely overweight patients with related medical problems. NBC's Tom Costello reports.

    Related stories on Vitals: 

    • FDA approves first weight-loss pill in 13 years
    • Desperate to qualify for weight-loss surgery, some patients pile on pounds
    • Could weight-loss surgery help end diabetes?

     

     

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  • 26
    Jun
    2012
    1:01pm, EDT

    Weight loss may boost men's testosterone

    By MyHealthNewsDaily.com staff

    For some men, weight loss plays an important role in raising low testosterone levels, a new study finds.

    In the study of overweight, middle-aged men with prediabetes, about half of those with low testosterone levels who attempted to lose weight by changing their lifestyle experienced an increase in their testosterone levels.

    The findings suggest "doctors should first encourage overweight men with low testosterone levels to try to lose weight through diet and exercise, before resorting to testosterone therapy to raise their hormone levels," said study researcher Dr. Frances Hayes, a professor at St. Vincent’s University Hospital, Dublin.

    Hayes and colleagues analyzed information from nearly 900 men with prediabetes — a condition in which blood sugar levels are abnormally high, but not high enough to be classified as Type 2 diabetes. The men's average age was 54.

    The men were randomly assigned to receive one of three treatments: the diabetes drug metformin, an inactive placebo pill or lifestyle modifications, which consisted of exercising for 150 minutes a week and eating less fat and fewer calories. The researchers said they considered men to have low testosterone if their levels were below 300 nanograms per deciliter of blood.

    Among the men assigned to change their lifestyle, about 20 percent had low testosterone levels at the study's start. After one year, that number fell to 11 percent.

    Among those taking metformin, 24.8 percent had low testosterone at the beginning of the study, and 23.8 percent still had the condition a year later. For the placebo group, the rate fell from 25.6 percent to 24.6 percent during the study.

    Men in the lifestyle modification group lost an average of about 17 pounds over the one-year study, and testosterone levels among men in this group increased 15 percent on average, the researchers said. (Men in the metformin group lost about 6 pounds.)

    "Losing weight not only reduces the risk of prediabetic men progressing to diabetes but also appears to increase their body's production of testosterone," Hayes said.

    The study was presented this week at the Endocrine Society’s annual Meeting in Houston.

    • Lose Weight Smartly: 7 Little-Known Tricks that Shave Pounds
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  • 3
    Apr
    2012
    1:30pm, EDT

    Most in U.S. get enough vitamins, nutrients

    By MyHealthNewsDaily Staff

    Americans may not eat the healthiest diets, but most get adequate levels of essential vitamins and nutrients, according to a new report from the Centers for Disease Control and Prevention.

    For most nutrients, less than 10 percent of the population is deficient, the report showed.

    However, deficiency rates vary by age, gender and ethnicity, and close to a third of African-Americans were deficient in vitamin D, the report said.

    These higher deficiency rates are a concern and need more attention, said study researcher Christine Pfeiffer, of the CDC’s National Center for Environmental Health.

    The report gave the results of an analysis of blood and urine samples collected from people between 2003 and 2006, measuring levels of 58 nutrient markers.

    For the U.S. as a whole, 10.5 percent of people were deficient in vitamin B6, 8.1 percent were deficient in vitamin D, 6.7 percent were deficient in iron, 6 percent were deficient in vitamin C, 2 percent were deficient in Vitamin B12, and less than 1 percent were deficient in vitamin A, E and folate.

    Vitamin D deficiency was 31 percent among African-Americans, 12 percent among Mexican-Americans and 3 percent among whites. Further research is needed to explain why non-Hispanic blacks have better bone health but yet have a higher rate of vitamin D deficiency, the report noted.

    Iodine levels among women ages 20 to 39 years may need improvement. This age group had iodine levels that were, on average, just above iodine insufficiency, the report said.

    Iodine is an essential component of thyroid hormones, which regulate growth and development. Iodine is especially important in women during childbearing years to ensure proper brain development of the fetus during pregnancy.

    The report found higher rates of iron deficiency among Mexican-American children ages 1 to 5 (11 percent), blacks (16 percent), and Mexican-American women of childbearing age (13 percent) when compared with other race/ethnic groups.

    One particular public health success story has been increases in folate levels in recent years. Blood folate levels in are 50 percent higher in all ethnic groups since the country began fortifying cereal-grain products with folic acid in 1998, the report said.

    The CDC plans to further analyze the data to identify the influence of socioeconomic and lifestyle factors on levels of nutrient levels, the agency said.

    • 9 Good Sources of Disease-Fighter Vitamin D
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    • 10 New Ways to Eat Well

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  • 28
    Nov
    2011
    4:33pm, EST

    Economy, diet rules curb Meals on Wheels programs

    U.S. Center for Nutrition Policy and Promotion

    The government issued a consumer brochure spelling out what the new guidelines mean. Click the cover for a full pdf version.

    By M. Alex Johnson, NBC News

    Federal guidelines meant to help Americans eat healthier foods are straining Meals on Wheels and other nonprofits already laboring to make sure the elderly get enough to eat at all.

    Lanakila Meals on Wheels in Honolulu, Hawaii, already has a waiting list of 90 people, most of them elderly, who have asked for food the organization can't afford to provide.

    The program can always use more volunteers, but what it really needs now is money.

    "We're looking for $120,000 just to maintain our existing programs and another $170,000 to meet the needs of the 90 people who are on our wait list," Lyn Moku, the program's director, told NBC station KHNL of Honolulu.

    "It's a real time of uncertainty," Moku said, because "everyone is having a hard time just with the way the economy is and unemployment."


    Some Meals on Wheels programs in the U.S. support themselves solely through donations and fundraisers, but many — like Lanakila Meals on Wheels — also rely on government funding. The Hawaii program says it gets about 60 percent of its funding from government sources.

    That government funding is also in question, for Lanakila Meals on Wheels and many other local chapters of the national nonprofit.

    The Health Trust, a charitable foundation in Campbell, Calif., reported that it has lost more $100,000 for its Meals on Wheels program. Most of that loss has come from government sources, and small corporate sponsorships haven't made up the difference.

    "It's tough. Times are very, very tough," said Enid A. Borden, president and chief executive of the Meals on Wheels Association of America.

    Last week, Meals on Wheels volunteers abandoned the traditional delivery of hot Thanksgiving meals to homes across Silicon Valley in Northern California. Instead, needy individuals — most of them elderly — received a frozen meal two days in advance that they had to thaw and heat themselves, NBC station KTVU of San Francisco/Oakland reported.

    Cut the salt; crunch the veggies
    It's not just the economy that's squeezing government outlays for community programs in general. Some are also being restricted by new federal nutrition guidelines that set standards for assistance programs.

    That means that when government agencies sit down to hand out community service grants, they have to consider the new guidelines when it comes to food programs like school lunches and Meals on Wheels.

    The guidelines drew a lot of attention for calling for a drastic reduction in salt consumption, especially among those 51 and older. But they also significantly changed the recommended ratio of proteins to fresh fruits and vegetables — putting much more emphasis on the latter.

    • Dietary Guidelines for Americans (.pdf)

    That requires new menus, new storage facilities to keep all that produce fresh and new ways to cook and deliver meals.

    Meeting the new requirements could be cost-prohibitive for Meals on Wheels in Bailey County, Texas, which could lose its funding from the regional association of governments, NBC station KCBD of Lubbock reported.

    Meals on Wheels for Lubbock itself isn't affected, said Lisa Gilliland, the program's assistant director, because it relies solely on donations and fundraisers. But in Bailey County, northwest of the city, and in many other areas across the country, funding could be at risk because "most of the smaller programs are government funded," she said.

    Borden told msnbc.com she is confident that Meals on Wheels will figure out a way to keep handing out the 1.7 million meals it delivers every day.

    "There are always things that are going to happen," she acknowledged. "We are always impacted when the price of anything goes up."

    But "one of the things I know is that our program will do whatever it needs to do to feed those seniors who are hungry," she said.

    "We are a resilient organization."

    Alex Johnson is a news and technology reporter for msnbc.com. Follow him on Twitter and Facebook.

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