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    17
    Apr
    2013
    12:51pm, EDT

    Deadly ricin: poisonous but clumsy weapon

    By Maggie Fox, Senior Writer, NBC News

    Ricin is a deadly poison and fairly easy to make, but it’s a crude and clumsy weapon, according to bioterror experts.

    A letter sent to President Barack Obama tested positive for ricin, officials said Wednesday, and it was sent by the same person who mailed a letter that tested positive for the poison to Mississippi Sen. Roger Wicker.

    Ricin is made from castor beans -- it’s a natural byproduct of making castor oil. When purified using sophisticated methods, it can be lethal and hard to trace. It’s best known as the poison used to kill Bulgarian journalist Georgi Markov in London in 1978 by an agent who poked him with an umbrella tipped with an injector.

    The U.S military also considered developing ricin as a biowarfare agent in the 1940s.

    Dr. Eric Toner of the Center for Biosecurity at the University of Pittsburgh Medical Center, says he doubts anything this sophisticated is involved in the letters sent to Wicker and the White House.

    “That is totally different from what we think is going on now, which is home-brewed ricin, not very potent,” Toner told NBC News. And Markov was killed by an injected pellet -- a much more certain method than putting powder into a letter.

    “It is not actually clear you can get anybody sick from ricin-containing letters,” Toner added. "It is probably a crackpot. It certainly is unsophisticated.”

    Recipes for making ricin abound online. But fiction aside -- in an episode of AMC's "Breaking Bad," Walter White whips some up -- it's not a big threat.

    “It’s been used many times mostly by domestic terrorists and lone wolves,” Toner said. “It is easy to make some ricin. You get some castor beans, make it in your kitchen, you can produce a batch of stuff that has some ricin in it. It is not very pure. It is not very potent. As near as we can tell it has never actually made anyone sick.”

    This week’s letters recall the anthrax attacks that killed five people and made 13 sick in October, 2001, after the Sept. 11 attacks. The anthrax attacks were very different, Toner says. They used highly purified anthrax spores -- living organisms that can get into the air and cover surfaces and that killed victims who breathed them in.

    When inhaled, anthrax spores can sprout in the lungs and pump out a poison. By the time victims start to become ill, it’s almost always too late to save them. Two of those who died were postal workers In Washington D.C.  who got infected after the spores got caught up in mail processing equipment.

    The attacks changed the way mail is processed in Washington and by some big companies -- media companies, including NBC, were also targeted by the attacks. Officials also installed "sniffers" around Washington, including in the Metro rail system and on the National Mall.

    “The federal government now screens all mail that comes to certain high-value locations,” Toner said.

    “It is my understanding that the screening tests, like all screening tests, are designed to be very sensitive but not necessarily specific.” That means that a false positive is possible, he said -- meaning the letters may not be tainted with ricin after all.

    Toner suspects more letters will turn up with the contamination. But unlike the anthrax spores, ricin powder isn’t likely to spread in the mail and sicken people, he says. In theory, ricin could be used to attack people in this way, according to the Centers for Disease Control and Prevention. It can be injected, used to poison food, or spread in the air as a fine powder.

    “Within a few hours of inhaling significant amounts of ricin, the likely symptoms would be respiratory distress (difficulty breathing), fever, cough, nausea, and tightness in the chest. Heavy sweating may follow as well as fluid building up in the lungs (pulmonary edema). This would make breathing even more difficult, and the skin might turn blue,” the CDC says.

    “If authorities suspect that people have inhaled ricin, a potential clue would be that a large number of people who had been close to each other rapidly developed fever, cough, and excess fluid in their lungs. These symptoms would likely be followed by severe breathing problems and possibly death.”

    There’s no antidote for ricin. The CDC advises anyone who thinks he or she may have been exposed to ricin to wash off as quickly as possible, breathe fresh air and seek medical care. Doctors may give intravenous fluids and perhaps charcoal to help people vomit any ricin they may have eaten.

    Related:

    • Police have suspect in ricin mailing
    • Case closed in anthrax attacks 
    • My anthrax survivor's story

    53 comments

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  • 10
    Sep
    2012
    3:55pm, EDT

    Britain warns heroin users after 2nd anthrax death

    By Kate Kelland, Reuters

    LONDON — British health authorities warned heroin users on Monday that the drug may be contaminated with anthrax after a second addict died of the infection in Blackpool, northwest England, within four weeks.

    The Health Protection Agency (HPA) said it presumed the source was contaminated heroin and that it was not clear whether the British cases were directly linked to eight other cases in Europe since early June.

    "This could be a source of infection if injected, smoked or snorted ... there is no safe route for consuming heroin or other drugs that may be contaminated with anthrax spores," the HPA said.

    Anthrax is a fairly common bacterium whose spores can be used as a biological weapon. Humans are rarely infected, but if the spores are inhaled, the disease can take hold quickly and by the time symptoms show, it can be too late for successful treatment with antibiotics.

    The Stockholm-based European Centre for Disease Prevention and Control (ECDC) and the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) say heroin users in Europe are still at risk of exposure to the infection.

    Four of the ten European cases have been in Britain, three in Germany, two in Denmark and one in France.

    "We urge all heroin users to seek urgent medical advice if they experience signs of infection such as redness or excessive swelling at or near an injection site, or ... high temperature, chills, severe headaches or breathing difficulties," HPA expert Fortune Ncube said in a statement.

    An outbreak of anthrax infections in 2009/2010 in Europe was also traced to contaminated heroin, but before then, only one case had been reported - in Norway in 2000.

    The infection is not transmitted directly from one person to another. It can come in several forms, including skin anthrax, lung anthrax - which has a 75 percent death rate - and gastrointestinal forms, all potentially deadly. 

    More from Vitals: 

    Private-school vaccine opt-outs rise

    FDA warns Iowa egg farm over salmonella

     

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    Explore related topics: anthrax, featured, infectious-diseases, addictions

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Maggie Fox, Senior Writer, NBC News

Senior health writer for NBCNews.com. With 20 years experience reporting on health, science, medicine and technology, Maggie now specializes in writing health stories that the average reader can understand. Former global health and science editor, Reuters, who established an award-winning and agenda-setting science and health file for the news agency.

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