Scientists use smart phones to get the poop on worm infestations

Isaac Bogoch/Toronto General Hospital

Scientists have used an iPhone and a simple US$8 lens to diagnose intestinal worm infections in rural Tanzania.

A cheap lens, flashlight and a little plastic wrap can turn a smart phone into a field microscope to test children for intestinal worms, researchers reported on Monday.

Microscopes are scarce in the countries where doctors often need them the most to figure out if children -- and often adults, too --are infested with worms that can cause anemia, stunt growth and cause other health problems.

Dr. Isaac Bogoch, an infectious disease specialist at Toronto General Hospital in Canada, had seen reports from scientists who turned their smart phones into microscopes. “There were a couple of papers that showed how certain groups were attaching the little ball lenses to their iPhones in a laboratory setting, and they were saying, ‘Hey, you can magnify specimens pretty easily,’” Bogoch told NBC News.

“We thought that this was a really good idea and we could take this into the field.”

For Bogoch and colleagues, into the field meant Pemba Island in Tanzania, where 199 children were already taking part in a clinical trial for a new treatment against intestinal worms.

“We are looking for very common parasites that affect over a billion people on the planet,” Bogoch says. “If untreated, they can lead to anemia and malnitrution and stunted cognitive and physical development.”

Right now, public health workers often simply guess. “Diagnosing these illnesses is a bit different in resource-poor settings because we apply population-based mass treatments so that only a small sample of the population is diagnosed in order to estimate the prevalence in a given endemic area,” says Dr. Peter Hotez, Dean of the National School of Tropical Medicine at the Baylor College of Medicine in Houston.

The World Health Organization then has guidelines for treating communities en masse if, say, 20 percent or more of those tested have a parasite. But that may mean treating children who don’t need the drugs, or treating them for the wrong parasite.

“Many rural health outposts have no diagnostic capability at all. They have no microscopes,” Bogoch says. “They do the best they can.”

They often simply guess about whether someone’s infested and if so, what with.

Bogoch and his colleagues bought an $8 lens off the Internet and used two-sided tape to attach it to his iPhone. They got stool samples on glass slides from the 199 children, wrapped them in cellophane, and used a flashlight to shine light up through the smear. They used the phone to magnify an image, and looked for parasite eggs.

They found evidence of intestinal worm in 70 percent of the samples that also tested positive using a microscope, the team reported in the American Journal of Tropical Medicine and Hygiene.

The method detected some worms better than others.  The doctors using it detected 81 percent of infections with giant roundworm, A. lumbricoides, and 54 percent of infections with another roundworm, T. trichiura. However, it could help spot only 14 percent of hookworm eggs.

But with a little tweaking, it could still help in places where there’s no diagnostic capability at all, said Hotez. And many people even in very poor countries carry smart phones.

Bogoch says another potential use could be to check blood smears for malaria parasites.

“If we do not have to bring in trained microscopists for this work it makes public health control more straightforward,” said Hotez, who was not involved in the study. “Developing simple hand-held devices could be an advance in the global control of neglected tropical diseases.”

As for the “ick” factor? “Obviously, the stool isn’t in direct contact with the phone,” said Bogoch. “Any time you are going to use it as a phone you will want to wash it down with an alcohol swab.”

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Discuss this post

It would be very easy to either make an iphone with a built-in microscope, a real "cool" factor if I say so myself, or have some entrepreneur manufacture a snap on attachment to sell for $10. I'm sure there are people tooling up as we speak and sending the order to China to get them made for 5 cents a piece.

Come on you engineering types, put your mind to this and design something like this!

  • 1 vote
Reply#1 - Mon Mar 11, 2013 6:51 PM EDT

It would be a better solution to show these countries how to build water treatment plants.Infected water which makes for infected soil that food is grown in accounts for many of these intestinal worms.

  • 1 vote
#1.1 - Thu Mar 14, 2013 11:33 PM EDT
Reply

So let me get this straight...you take a dump on a piece of plastic wrap then smear it on your phone camera lens then shine a flashlight on it to look at worms. I just go out to the sidewalk after it rains and look at worms. Of course it has benefits if you like to go fishing...you don't need to hit the bait store...

    Reply#2 - Mon Mar 11, 2013 7:09 PM EDT

    Right, so there are no $50 microscopes in Tanzania, but $600 iphones are abundant. Please, get real (there is no app for that)

    • 3 votes
    Reply#3 - Mon Mar 11, 2013 9:14 PM EDT

    iPhones everywhere, worms everywhere, microscopes aren't.

    Which iPhone did you get?

      #3.1 - Mon Mar 11, 2013 10:53 PM EDT

      I'm not sure about Iphones, but when my sister was in Malawi last year, she said that just about EVERYONE (even those who were quite poor) had cell phones. In fact, they often used them as flashlights during things like church services when the power would go out. I don't know about Tanzania, but perhaps it is similar.

      • 1 vote
      #3.2 - Tue Mar 12, 2013 12:14 PM EDT

      It's a matter of cell phone towers being installed in these poorer countries by companies and entrepreneurs. Most don't have landline services installed but it was businessmen seeing an opportunity to enter a wide open market. Once cell towers are in, you start selling everybody phones at various price levels. Soon even some of the poorest have a phone.

      It's like the old story: two shoe salesman go to a third world country. One salesman calls the home office in the U.S. and says, "It's no good. We can't sell here. Nobody wears shoes here." The other salesman calls back home enthusiastically saying, "This is great! Nobody wears shoes here yet. We've got a whole new market to sell to!"

      • 1 vote
      #3.3 - Wed Mar 13, 2013 10:37 AM EDT

      This is totally idiotic. People in poor rural areas do NOT have iPhones. They may have cell phones, and maybe even low quality smartphones, but not phones with cameras as high in quality as the iPhone. Certainly WAY cheaper to buy a basic microscope.

      • 1 vote
      #3.4 - Thu Mar 14, 2013 8:37 AM EDT
      Reply

      congitive

      Apparently some other things can impact cognitive development. Perhaps a handy spell checker would help.

      • 1 vote
      Reply#4 - Tue Mar 12, 2013 9:58 AM EDT

      Pretty @!$%#ty way to use a smart phone!

      • 1 vote
      Reply#5 - Tue Mar 12, 2013 11:22 AM EDT

      when they mentioned parasite i thought they were talking about the US congress

      • 1 vote
      Reply#6 - Tue Mar 12, 2013 11:47 AM EDT

      MSNBC just has to get in their daily poop story for the anal fixated, some way, some how, courtisy " Writings From The Bathroom Wall" dept.

      • 1 vote
      Reply#7 - Tue Mar 12, 2013 11:49 AM EDT

      But then, they also insist on classifying video games as "Science and Technology" instead of "Entertainment" so maybe I should not expect too much of them.

        #7.1 - Tue Mar 12, 2013 11:53 AM EDT

        Right. Because video games are never on the cutting edge of technology.

          #7.2 - Wed Mar 13, 2013 7:59 AM EDT
          Reply

          DAMN.....not to many comments on this subject...can't think of any more jokes... :-(

            Reply#8 - Tue Mar 12, 2013 5:08 PM EDT
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