Pill to stop gray hair could pose risks, doctors caution

George Clooney may be able to rock the sexy salt-and-pepper look, but most non-famous people want to avoid gray hair as long as possible. That's why cosmetic giant L'Oreal's recent claim that it's developing a pill to prevent gray hair is getting so much attention.

But don't get too excited yet about keeping your luxurious dark locks — or blond or red — forever. Some doctors say the anti-gray supplement, which the company has been experimenting with for more than a decade, could pose risks.

The pill, scheduled to become available in 2015, contains an undisclosed fruit extract that mimics the chemical tyrosinase-related protein or TRP-2, an enzyme that protects pigmentation production, the company has said. The goal of the fruit extract pill is to prevent oxidative stress, a process that occurs when hair cells succumb to antioxidants and turn gray, L’Oreal officials say.

If you’re already fighting those coarse gray strands, the pill won’t help. According to L'Oreal, patients will have to take it every day for at least 10 years before hair starts turning gray and it will have to be taken for life — or until you decide to embrace the silver fox style.

However, most people don’t know when they’re going to go gray, especially not 10 years in advance, experts note. People can start turning gray anywhere from the mid-30s to their 40s. Some can begin to go prematurely gray in their early 20s. Then there are the lucky ones.

“There are some people who never go gray,” says Dr. Maria Colavincenzo, assistant professor of dermatology at Northwestern University Feinberg School of Medicine. “What’s the point of taking a pill 10 years before you need and take it forever if you’re never going to turn gray? “It’s probably going to be a long time before this is going to become a reality in this country.”

Still, given the expense and tedium of regularly hiding gray hair, there could be plenty of people who will want the medication, even if it means popping a pill for the rest of their lives, says Dr. Hillary Johnson, director of dermatologic surgery at Weill Cornell Medical College Department of Dermatology.

“Lots of men take Propecia tablets to prevent balding and they take that for the rest of their lives,” Johnson says. “They would have to be a highly-motivated group of people, but broadly, that motivation is going to be hard to come by.”

The dermatologists say there are a number of safety concerns with the drug.

“How is it going to affect the skin and the organs?” Colavincenzo wonders. “You can put anything in a capsule and market it as making your hair grow back and someone will buy it. I get upset about a vulnerable market — and people worried about going gray are going to go for this.”

“It would make me warn patients to be extra careful [about taking it],” Johnson says. “Anything for cosmetic purposes goes with extra caution because it’s not something a person has to have, and it’s not worth the risk.”

Related:

Science of the silver fox: Why hair goes gray

Discuss this post

The article states: "The goal of the fruit extract pill is to prevent oxidative stress, a process that occurs when hair cells succumb to antioxidants and turn gray, L’Oreal officials say."

I believe the article should state: "...when hair cells succumb to oxidants" - not antioxidants. The oxidants turn the hair gray. Antioxidants, such as the fruit extract, reduce stress caused by oxidation.

  • 1 vote
Reply#1 - Mon Oct 10, 2011 9:37 AM EDT

Oh Bummer..you can't have gray hair already>>what's up with that?

 

  • 1 vote
Reply#2 - Mon Oct 10, 2011 12:55 PM EDT

I can't see 20-somethings and 30-somethings taking a pill for life to prevent gray hair. Most people hate taking even a multi-vitamin every day. Sounds like a total waste of money.

  • 1 vote
Reply#3 - Mon Oct 10, 2011 6:09 PM EDT

hey do they have one that does just the opposite? I want my silvering hair, (sorry it's silver, not grey) to finish turning NOW! Not wait until I'm 76 for it to be all silver. It's still mostly black and I have it blond to hide the silver, (works great and looks good too) but hey if it would all turn silver then I wouldn't have to get it bleached!

but I'm not going to take a pill to turn it silver for the rest of my life, how silly is that!

  • 1 vote
Reply#4 - Tue Oct 11, 2011 12:14 PM EDT

The chinese herb fo-ti/hu-shou-wu, is supposed to remedy grey hair and is available in some American health food stores - as well as in some stores in various china towns.

  • 1 vote
Reply#5 - Tue Oct 11, 2011 1:14 PM EDT
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